GrippeAllemagneV4, Main, Exploration, bibRecord, 000023

Analysis of acute respiratory infections due to influenza virus A, B and RSV during an influenza epidemic 2018.

Identifieur interne : 000023 ( Main/Exploration ); précédent : 000022; suivant : 000024

Analysis of acute respiratory infections due to influenza virus A, B and RSV during an influenza epidemic 2018.

Auteurs : Spiridon Topoulos [Allemagne] ; Christian Giesa [Allemagne] ; Sören Gatermann [Allemagne] ; Rene Fussen [Allemagne] ; Sebastian Lemmen [Allemagne] ; Santiago Ewig [Allemagne]

Source :

Infection [ 1439-0973 ] ; 2019.

RBID : pubmed:30649684

Descripteurs français

KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Allemagne (épidémiologie), Co-infection (mortalité), Co-infection (virologie), Co-infection (épidémiologie), Femelle (MeSH), Grippe humaine (mortalité), Grippe humaine (virologie), Grippe humaine (épidémiologie), Hospitalisation (statistiques et données numériques), Humains (MeSH), Infection croisée (mortalité), Infection croisée (virologie), Infection croisée (épidémiologie), Infections à virus respiratoire syncytial (mortalité), Infections à virus respiratoire syncytial (virologie), Infections à virus respiratoire syncytial (épidémiologie), Jeune adulte (MeSH), Maladie aigüe (mortalité), Maladie aigüe (épidémiologie), Morbidité (MeSH), Mâle (MeSH), Sujet âgé (MeSH), Virus de la grippe A (physiologie), Virus influenza B (physiologie), Virus respiratoires syncytiaux (physiologie), Épidémies (MeSH), Études rétrospectives (MeSH).
MESH :
- mortalité : Co-infection, Grippe humaine, Infection croisée, Infections à virus respiratoire syncytial, Maladie aigüe.
- physiologie : Virus de la grippe A, Virus influenza B, Virus respiratoires syncytiaux.
- statistiques et données numériques : Hospitalisation.
- virologie : Co-infection, Grippe humaine, Infection croisée, Infections à virus respiratoire syncytial.
- épidémiologie : Allemagne, Co-infection, Grippe humaine, Infection croisée, Infections à virus respiratoire syncytial, Maladie aigüe.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Jeune adulte, Morbidité, Mâle, Sujet âgé, Épidémies, Études rétrospectives.
Wicri :
- geographic : Allemagne.

English descriptors

KwdEn :
- Acute Disease (epidemiology), Acute Disease (mortality), Adult (MeSH), Aged (MeSH), Coinfection (epidemiology), Coinfection (mortality), Coinfection (virology), Cross Infection (epidemiology), Cross Infection (mortality), Cross Infection (virology), Epidemics (MeSH), Female (MeSH), Germany (epidemiology), Hospitalization (statistics & numerical data), Humans (MeSH), Influenza A virus (physiology), Influenza B virus (physiology), Influenza, Human (epidemiology), Influenza, Human (mortality), Influenza, Human (virology), Male (MeSH), Middle Aged (MeSH), Morbidity (MeSH), Respiratory Syncytial Virus Infections (epidemiology), Respiratory Syncytial Virus Infections (mortality), Respiratory Syncytial Virus Infections (virology), Respiratory Syncytial Viruses (physiology), Retrospective Studies (MeSH), Young Adult (MeSH).
MESH :
- geographic , epidemiology : Germany.
- epidemiology : Acute Disease, Coinfection, Cross Infection, Influenza, Human, Respiratory Syncytial Virus Infections.
- mortality : Acute Disease, Coinfection, Cross Infection, Influenza, Human, Respiratory Syncytial Virus Infections.
- physiology : Influenza A virus, Influenza B virus, Respiratory Syncytial Viruses.
- statistics & numerical data : Hospitalization.
- virology : Coinfection, Cross Infection, Influenza, Human, Respiratory Syncytial Virus Infections.
- Adult, Aged, Epidemics, Female, Humans, Male, Middle Aged, Morbidity, Retrospective Studies, Young Adult.

Abstract

PURPOSE

We studied the incidence, morbidity and mortality of all patients presenting in our teaching hospital with proven influenza virus and/or respiratory syncytial virus (RSV) infection during the influenza epidemic season 2018 which was characterized by a predominant incidence of influenza virus B type B of the Yamagata line.

METHODS

In the fall of 2017, specific precaution measures in addition to standard measures were implemented, including standardized testing for influenza virus A,B and RSV by multiplex PCR of pharyngeal swabsData from all consecutive patients were analyzed retrospectively.

RESULTS

Overall 651 patients were examined for the presence of influenza virus and RSV; 214 patients had influenza virus A (n = 36), B (n = 152), and/or RSV (n = 30), including four patients with dual infection. 86% of cases had influenza virus (80% B), and 14% RSV infection. N = 23 cases were treated as outpatients. The rate of acute viral respiratory infections (influenza virus and RSV) was 191 of 2776 (6.9%) admissions to medical wards. Of n = 191 hospitalized cases, n = 44 cases (20.6%) had nosocomial infection. Viral infections were associated with a high morbidity (pneumonia 28.5%, mortality 4.7%). Independent predictors of prolonged hospitalization were the presence of pneumonia, NIV and renal complications, and independent predictors of pneumonia were age ≥ 65 years, bedridden status and CRP ≥ 2.9 mg/dL.

CONCLUSIONS

The rate of nosocomial cases was high despite established precaution measures. RSV was associated with morbidity and mortality comparable to influenza. Pneumonia remains the main complication of acute viral respiratory infections, and antimicrobial treatment should include both antiviral as well as antibacterial agents.

DOI: 10.1007/s15010-018-1262-x
PubMed: 30649684

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000021
to stream Main, to step Curation: 000021

Le document en format XML

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<series><title level="j">Infection</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute Disease (epidemiology)</term>
<term>Acute Disease (mortality)</term>
<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Coinfection (epidemiology)</term>
<term>Coinfection (mortality)</term>
<term>Coinfection (virology)</term>
<term>Cross Infection (epidemiology)</term>
<term>Cross Infection (mortality)</term>
<term>Cross Infection (virology)</term>
<term>Epidemics (MeSH)</term>
<term>Female (MeSH)</term>
<term>Germany (epidemiology)</term>
<term>Hospitalization (statistics & numerical data)</term>
<term>Humans (MeSH)</term>
<term>Influenza A virus (physiology)</term>
<term>Influenza B virus (physiology)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (mortality)</term>
<term>Influenza, Human (virology)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Morbidity (MeSH)</term>
<term>Respiratory Syncytial Virus Infections (epidemiology)</term>
<term>Respiratory Syncytial Virus Infections (mortality)</term>
<term>Respiratory Syncytial Virus Infections (virology)</term>
<term>Respiratory Syncytial Viruses (physiology)</term>
<term>Retrospective Studies (MeSH)</term>
<term>Young Adult (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Allemagne (épidémiologie)</term>
<term>Co-infection (mortalité)</term>
<term>Co-infection (virologie)</term>
<term>Co-infection (épidémiologie)</term>
<term>Femelle (MeSH)</term>
<term>Grippe humaine (mortalité)</term>
<term>Grippe humaine (virologie)</term>
<term>Grippe humaine (épidémiologie)</term>
<term>Hospitalisation (statistiques et données numériques)</term>
<term>Humains (MeSH)</term>
<term>Infection croisée (mortalité)</term>
<term>Infection croisée (virologie)</term>
<term>Infection croisée (épidémiologie)</term>
<term>Infections à virus respiratoire syncytial (mortalité)</term>
<term>Infections à virus respiratoire syncytial (virologie)</term>
<term>Infections à virus respiratoire syncytial (épidémiologie)</term>
<term>Jeune adulte (MeSH)</term>
<term>Maladie aigüe (mortalité)</term>
<term>Maladie aigüe (épidémiologie)</term>
<term>Morbidité (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Virus de la grippe A (physiologie)</term>
<term>Virus influenza B (physiologie)</term>
<term>Virus respiratoires syncytiaux (physiologie)</term>
<term>Épidémies (MeSH)</term>
<term>Études rétrospectives (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Germany</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Acute Disease</term>
<term>Coinfection</term>
<term>Cross Infection</term>
<term>Influenza, Human</term>
<term>Respiratory Syncytial Virus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Acute Disease</term>
<term>Coinfection</term>
<term>Cross Infection</term>
<term>Influenza, Human</term>
<term>Respiratory Syncytial Virus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Co-infection</term>
<term>Grippe humaine</term>
<term>Infection croisée</term>
<term>Infections à virus respiratoire syncytial</term>
<term>Maladie aigüe</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Virus de la grippe A</term>
<term>Virus influenza B</term>
<term>Virus respiratoires syncytiaux</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Influenza A virus</term>
<term>Influenza B virus</term>
<term>Respiratory Syncytial Viruses</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Hospitalization</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Hospitalisation</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Co-infection</term>
<term>Grippe humaine</term>
<term>Infection croisée</term>
<term>Infections à virus respiratoire syncytial</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coinfection</term>
<term>Cross Infection</term>
<term>Influenza, Human</term>
<term>Respiratory Syncytial Virus Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Allemagne</term>
<term>Co-infection</term>
<term>Grippe humaine</term>
<term>Infection croisée</term>
<term>Infections à virus respiratoire syncytial</term>
<term>Maladie aigüe</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Epidemics</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Morbidity</term>
<term>Retrospective Studies</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Morbidité</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Épidémies</term>
<term>Études rétrospectives</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Allemagne</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>PURPOSE</b>
</p>
<p>We studied the incidence, morbidity and mortality of all patients presenting in our teaching hospital with proven influenza virus and/or respiratory syncytial virus (RSV) infection during the influenza epidemic season 2018 which was characterized by a predominant incidence of influenza virus B type B of the Yamagata line.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>In the fall of 2017, specific precaution measures in addition to standard measures were implemented, including standardized testing for influenza virus A,B and RSV by multiplex PCR of pharyngeal swabsData from all consecutive patients were analyzed retrospectively.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>Overall 651 patients were examined for the presence of influenza virus and RSV; 214 patients had influenza virus A (n = 36), B (n = 152), and/or RSV (n = 30), including four patients with dual infection. 86% of cases had influenza virus (80% B), and 14% RSV infection. N = 23 cases were treated as outpatients. The rate of acute viral respiratory infections (influenza virus and RSV) was 191 of 2776 (6.9%) admissions to medical wards. Of n = 191 hospitalized cases, n = 44 cases (20.6%) had nosocomial infection. Viral infections were associated with a high morbidity (pneumonia 28.5%, mortality 4.7%). Independent predictors of prolonged hospitalization were the presence of pneumonia, NIV and renal complications, and independent predictors of pneumonia were age ≥ 65 years, bedridden status and CRP ≥ 2.9 mg/dL.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>The rate of nosocomial cases was high despite established precaution measures. RSV was associated with morbidity and mortality comparable to influenza. Pneumonia remains the main complication of acute viral respiratory infections, and antimicrobial treatment should include both antiviral as well as antibacterial agents.</p>
</div>
</front>
</TEI>
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<DateCompleted><Year>2019</Year>
<Month>08</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>02</Month>
<Day>25</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1439-0973</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>47</Volume>
<Issue>3</Issue>
<PubDate><Year>2019</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Infection</Title>
<ISOAbbreviation>Infection</ISOAbbreviation>
</Journal>
<ArticleTitle>Analysis of acute respiratory infections due to influenza virus A, B and RSV during an influenza epidemic 2018.</ArticleTitle>
<Pagination><MedlinePgn>425-433</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s15010-018-1262-x</ELocationID>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">We studied the incidence, morbidity and mortality of all patients presenting in our teaching hospital with proven influenza virus and/or respiratory syncytial virus (RSV) infection during the influenza epidemic season 2018 which was characterized by a predominant incidence of influenza virus B type B of the Yamagata line.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">In the fall of 2017, specific precaution measures in addition to standard measures were implemented, including standardized testing for influenza virus A,B and RSV by multiplex PCR of pharyngeal swabsData from all consecutive patients were analyzed retrospectively.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Overall 651 patients were examined for the presence of influenza virus and RSV; 214 patients had influenza virus A (n = 36), B (n = 152), and/or RSV (n = 30), including four patients with dual infection. 86% of cases had influenza virus (80% B), and 14% RSV infection. N = 23 cases were treated as outpatients. The rate of acute viral respiratory infections (influenza virus and RSV) was 191 of 2776 (6.9%) admissions to medical wards. Of n = 191 hospitalized cases, n = 44 cases (20.6%) had nosocomial infection. Viral infections were associated with a high morbidity (pneumonia 28.5%, mortality 4.7%). Independent predictors of prolonged hospitalization were the presence of pneumonia, NIV and renal complications, and independent predictors of pneumonia were age ≥ 65 years, bedridden status and CRP ≥ 2.9 mg/dL.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The rate of nosocomial cases was high despite established precaution measures. RSV was associated with morbidity and mortality comparable to influenza. Pneumonia remains the main complication of acute viral respiratory infections, and antimicrobial treatment should include both antiviral as well as antibacterial agents.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Topoulos</LastName>
<ForeName>Spiridon</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Kliniken für Pneumologie und Infektiologie, EVK Herne und Augusta-Kranken-Anstalt Bochum, Thoraxzentrum Ruhrgebiet, Bergstrasse 26, 44791, Bochum, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Giesa</LastName>
<ForeName>Christian</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Kliniken für Pneumologie und Infektiologie, EVK Herne und Augusta-Kranken-Anstalt Bochum, Thoraxzentrum Ruhrgebiet, Bergstrasse 26, 44791, Bochum, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gatermann</LastName>
<ForeName>Sören</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Ruhr-Universität Bochum, Institut für Mikrobiologie (IML), Bochum, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fussen</LastName>
<ForeName>Rene</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Zentralbereich für Krankenhaushygiene und Infektiologie, Universitätsklinikum Aachen, Aachen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lemmen</LastName>
<ForeName>Sebastian</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Zentralbereich für Krankenhaushygiene und Infektiologie, Universitätsklinikum Aachen, Aachen, Germany.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ewig</LastName>
<ForeName>Santiago</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Kliniken für Pneumologie und Infektiologie, EVK Herne und Augusta-Kranken-Anstalt Bochum, Thoraxzentrum Ruhrgebiet, Bergstrasse 26, 44791, Bochum, Germany. ewig@augusta-bochum.de.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2019</Year>
<Month>01</Month>
<Day>16</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Germany</Country>
<MedlineTA>Infection</MedlineTA>
<NlmUniqueID>0365307</NlmUniqueID>
<ISSNLinking>0300-8126</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000208" MajorTopicYN="N">Acute Disease</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D060085" MajorTopicYN="N">Coinfection</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003428" MajorTopicYN="N">Cross Infection</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D058872" MajorTopicYN="Y">Epidemics</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009980" MajorTopicYN="N">Influenza A virus</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009981" MajorTopicYN="N">Influenza B virus</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007251" MajorTopicYN="N">Influenza, Human</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009017" MajorTopicYN="N">Morbidity</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018357" MajorTopicYN="N">Respiratory Syncytial Virus Infections</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName>
<QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012136" MajorTopicYN="N">Respiratory Syncytial Viruses</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Coinfection</Keyword>
<Keyword MajorTopicYN="N">Influenza epidemic</Keyword>
<Keyword MajorTopicYN="N">Pneumonia</Keyword>
<Keyword MajorTopicYN="N">Viral respiratory tract infection</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year>
<Month>09</Month>
<Day>15</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>12</Month>
<Day>18</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2019</Year>
<Month>1</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2019</Year>
<Month>8</Month>
<Day>31</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2019</Year>
<Month>1</Month>
<Day>17</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
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<affiliations><list><country><li>Allemagne</li>
</country>
<region><li>District de Cologne</li>
<li>Rhénanie-du-Nord-Westphalie</li>
</region>
<settlement><li>Aix-la-Chapelle</li>
</settlement>
</list>
<tree><country name="Allemagne"><noRegion><name sortKey="Topoulos, Spiridon" sort="Topoulos, Spiridon" uniqKey="Topoulos S" first="Spiridon" last="Topoulos">Spiridon Topoulos</name>
</noRegion>
<name sortKey="Ewig, Santiago" sort="Ewig, Santiago" uniqKey="Ewig S" first="Santiago" last="Ewig">Santiago Ewig</name>
<name sortKey="Fussen, Rene" sort="Fussen, Rene" uniqKey="Fussen R" first="Rene" last="Fussen">Rene Fussen</name>
<name sortKey="Gatermann, Soren" sort="Gatermann, Soren" uniqKey="Gatermann S" first="Sören" last="Gatermann">Sören Gatermann</name>
<name sortKey="Giesa, Christian" sort="Giesa, Christian" uniqKey="Giesa C" first="Christian" last="Giesa">Christian Giesa</name>
<name sortKey="Lemmen, Sebastian" sort="Lemmen, Sebastian" uniqKey="Lemmen S" first="Sebastian" last="Lemmen">Sebastian Lemmen</name>
</country>
</tree>
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Analysis of acute respiratory infections due to influenza virus A, B and RSV during an influenza epidemic 2018.

Analysis of acute respiratory infections due to influenza virus A, B and RSV during an influenza epidemic 2018.

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